In the middle of Nowheresville lives 16-year-old Mike who wants out of his crappy life - permanently! Spending his time devising ways to do himself in, he considers the fatal brain tumor in his head as a godsend. That changes when he meets a girl and falls in love for the first time - without even knowing what love is.
An ambitious lawyer kills her gardener by mistake, fearing her chances with the law and the impact this will have on her career at a prestigious firm, she turns to her best friend to help her get rid of the body.
When an image-conscious wild child takes a strange new drug at a party, she undergoes a shocking transformation. Desperate to reverse the effects of the drug, she is horrified to discover that she has become the key to saving the human race.